Sotirios received his professional degree in architecture at the Irwin S. Chanin School of Architecture of the Cooper Union in New York. He received his M.Arch studying history and theory of architecture with Alberto Pérez-Gómez at McGill University, Montreal. His book, Space Out (edited by Lebbeus Woods and published by the Research Institute for Experimental Architecture in their book series with Springer Verlag, 2005) explores the spatial and material dimension of invisible and immeasurable electromagnetic phenomena. Sotirios has worked on several urban design and architecture projects in Israel, USA, China and Dubai. He was the recipient of the Abraham E. Kazan award for Urban Design Studies in New York City.
While continuing to work in New York and Europe, he also manages and supervises specialized masonry construction projects in Canada and executes national certified masonry building technology research and development on old and new buildings. He recently supervised the masonry construction at the Wuskwatim Hydroelectric dam in Northern Canada. He was a research consultant at the Cooper Union Institute for Sustainable Design in New York City for the Lessons from Modernism exhibition that studied sustainable details and concepts in early modern architecture. Sotirios was visiting professor at the University of Puerto Rico, and the Polytechnic University of Puerto Rico where he taught graduate and undergraduate design, urban architecture, and a graduate history and theory of architecture seminar. He taught a joint graduate design studio with the UPR in San Juan and MIT in Boston with Nader Tehrani and Jose Javier Toro. He currently teaches at the University of Manitoba School of Architecture. He serves on the board of directors at the Winnipeg Symphony Orchestra, is the president of Plug In Institute of Contemporary Art, and board chair of Basilica Hudson, in Hudson New York. Currently, he is designing and building projects in Winnipeg, New York, and Greece.